This one has been picked apart for ages; does the briefcase contain Marsellus Wallace' soul? Doesn't matter at the end of the day—just moves the plot along.
The entire movie is spent trying to figure out the meaning behind the last word Kane uttered, "Rosebud." The name of his sled, it's metaphorical for the life he turned his back on.
The bachelor party loses the groom and spends the entire movie trying to find him...and figure out what the heck happened the prior night. Is Doug a character or a plot device? Both?
"That rug really tied the room together."
Maybe one of the most beloved lines in cinema; when the Dude's life is thrown into chaos, it's all because of a kidnapping (also a MacGuffin) and a Persian rug that...
Talk about a high stakes MacGuffin. This biblical artifact is pursued by both Indiana Jones and the Nazis—the driving force behind Raiders, obviously.
When an object is the film's title, it might just be a MacGuffin.
The infinity stones play a HUGE role in the Marvel cinematic universe. They unite the guardians of the galaxy, empower Loki, etc.In Infinity War (and Endgame) everyone is after them.