Zurer, who has appeared in Munich and was last seen in Vantage Point, will star opposite Tom Hanks in the Ron Howard-directed film. Naomi Watts was previously reported as being attached to the role.
Zurer's character is the daughter of CERN physicist Leonardo Vetra. Following her father's death, Vittoria pairs with Robert Langdon (Hanks) on a journey to uncover the mystery behind her father's murder and stop a terrorist plot.
Filming is set to begin in Europe in June for a May 15, 2009 release.